Optimization of Ritalin for more Effective Results Essay -- Methylphen

Ritalin (Methylphenidate) Optimization Ritalin Pills Abstract: Attention-deficit hyperactivity disorder (ADHD) is currently the dominating psychiatric disorder found in children. The creation of the drug Ritalin based on the molecule Methylphenidate in the early 90’s sparked a widespread use of this psycho stimulant, which still remains as one of the most popular drugs used to counteract the symptoms of ADHD. My ultimate goal in this research project is to design analogs for the drug Ritalin in the hopes of discovering a more effective version of this medication. Through research, it can be concluded that none the analogs suggested are suitable candidates for new drugs based on the results. Introduction: With 3-5 percent of school children today diagnosed with attention-deficit hyperactivity disorder (ADHD), ADHD has been reported to account for 50 percent of the child psychiatric population seen at the clinic. Methylphenidate (figure 1) serves as the dominant drug used in medications counteracting the symptoms of ADHD. (1) Among those medications, Ritalin is currently prescribed for daily use to 1.5 million school children in the United States, making it one of the most widely used prescription medications today. (2) The optimization of Ritalin is of utmost importance and will therefore, be the topic of this project. Scientists believe that ADHD is caused by an imbalance between dopaminergic, noradrenergic and serotonergic neurotransmitter systems. However, this theory remains questionable due to an insufficient amount of evidence. Methylphenidate’s mechanism of action, Fig. 1: Methylphenidate Molecular Structure which is based on dopamine synaptic uptake inhibition, essentially allows it to binds to ... ... Wiley & Sons, Ltd. (1997) 29 July 2008 2) Ritalin: Fast Facts. Do It Now Foundation. 29 July 2008. figure 1: United States Environmental Protection Agency. July 28 2008. figure 2: Medscape. July 28 2008. title picture: Wikimedia. July 28 2008. figure 4: Wikipedia. July 28 2008. figure 5: Wikipedia. July 28 2008. %28primary%29-skeletal.png> figure 8: Wikipedia. July 28 2008. svg> Optimization of Ritalin for more Effective Results Essay -- Methylphen Ritalin (Methylphenidate) Optimization Ritalin Pills Abstract: Attention-deficit hyperactivity disorder (ADHD) is currently the dominating psychiatric disorder found in children. The creation of the drug Ritalin based on the molecule Methylphenidate in the early 90’s sparked a widespread use of this psycho stimulant, which still remains as one of the most popular drugs used to counteract the symptoms of ADHD. My ultimate goal in this research project is to design analogs for the drug Ritalin in the hopes of discovering a more effective version of this medication. Through research, it can be concluded that none the analogs suggested are suitable candidates for new drugs based on the results. Introduction: With 3-5 percent of school children today diagnosed with attention-deficit hyperactivity disorder (ADHD), ADHD has been reported to account for 50 percent of the child psychiatric population seen at the clinic. Methylphenidate (figure 1) serves as the dominant drug used in medications counteracting the symptoms of ADHD. (1) Among those medications, Ritalin is currently prescribed for daily use to 1.5 million school children in the United States, making it one of the most widely used prescription medications today. (2) The optimization of Ritalin is of utmost importance and will therefore, be the topic of this project. Scientists believe that ADHD is caused by an imbalance between dopaminergic, noradrenergic and serotonergic neurotransmitter systems. However, this theory remains questionable due to an insufficient amount of evidence. Methylphenidate’s mechanism of action, Fig. 1: Methylphenidate Molecular Structure which is based on dopamine synaptic uptake inhibition, essentially allows it to binds to ... ... Wiley & Sons, Ltd. (1997) 29 July 2008 2) Ritalin: Fast Facts. Do It Now Foundation. 29 July 2008. figure 1: United States Environmental Protection Agency. July 28 2008. figure 2: Medscape. July 28 2008. title picture: Wikimedia. July 28 2008. figure 4: Wikipedia. July 28 2008. figure 5: Wikipedia. July 28 2008. %28primary%29-skeletal.png> figure 8: Wikipedia. July 28 2008. svg>